Computational modeling of cytokine signaling in microglia
نویسندگان
چکیده
منابع مشابه
Computational modeling of cytokine signaling in microglia.
Neuroinflammation due to glial activation has been linked to many CNS diseases. We developed a computational model of a microglial cytokine interaction network to study the regulatory mechanisms of microglia-mediated neuroinflammation. We established a literature-based cytokine network, including TNFα, TGFβ, and IL-10, and fitted a mathematical model to published data from LPS-treated microglia...
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ژورنال
عنوان ژورنال: Molecular BioSystems
سال: 2015
ISSN: 1742-206X,1742-2051
DOI: 10.1039/c5mb00488h